منابع مشابه
Cell therapy - showing cells the way home
The clinical potential of cell-based therapies is limited by poor targeting of systemically infused cells to diseased tissues [1]. In our recent study, we have developed a multi-step screening platform to identify small molecules that boost the homing properties of mesenchymal stem cells (MSCs) to sites of inflammation [2]. First, a medium-throughput screen was designed to identify small molecu...
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Lighthouse is an on-line interface for a Web-based information retrieval system. It accepts queries from a user, collects the retrieved documents from the search engine, organizes and presents them to the user. The system integrates two known presentations of the retrieved results – the ranked list and clustering visualization – in a novel and effective way. It accepts the user’s input and adju...
متن کاملFinding our way home
Eleven years ago, my wife and I lost our son Callum to cancer. He had just celebrated his 3 birthday at Sick Kids Hospital in Toronto where he was undergoing his 3 “rescue” stem cell transplant for his 6 and final chemotherapy cycle, following the surgical removal of a brain tumor. The image above is a plaster imprint of Callum’s untouched foot, and was created on November 11, 2006 – just momen...
متن کاملSmart Signs: Showing the way in Smart Surroundings
This paper presents a context-aware guidance and messaging system for large buildings and surrounding venues. Smart Signs are a new type of electronic doorand way-sign based on wireless sensor networks. Smart Signs present in-situ personalized guidance and messages, are ubiquitous, and easy to understand. They combine the easiness of use of traditional static signs with the flexibility and reac...
متن کاملShowing the Way: Oncolytic Adenoviruses as Chaperones of Immunostimulatory Adjuncts
Oncolytic adenoviruses (OAds) are increasingly recognized as vectors for immunotherapy in the treatment of various solid tumors. The myriads of advantages of using adenovirus include targeted specificity upon infection and selective replication, which lead to localized viral burst, exponential spread of OAds, and antitumor effect. OAds can also induce a strong immune reaction due to the massive...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2006
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc1868